Redox Biology Center

The Nebraska Redox Biology Center is a world-class interdisciplinary research hub dedicated to understanding the fundamental roles of oxidation-reduction (redox) processes in biological systems.

Located at the University of Nebraska-Lincoln, the center brings together leading researchers from the fields of biological chemistry, molecular cell biology, medicine, and related fields that seek to uncover the complex roles of redox reactions in biology and human health. Through cutting-edge research and collaborations, the Redox Biology Center is at the forefront of advancing the field of basic redox biology and developing new biotechnological, diagnostic, and therapeutic applications.

The Nebraska Redox Biology Center (RBC) at the University of Nebraska-Lincoln was established in 2002 as a collaborative research center with the University of Nebraska Medical Center (UNMC). Originally funded by a National Institutes of Health (NIH) P20 RR017675 COBRE grant, the RBC has since graduated to self-sufficiency and focuses on fundamental questions in redox biology, investigating how cells maintain the balance between oxidation and reduction reactions (also known as redox homeostasis). The RBC combines the expertise and facilities of the UNL and UNMC in a collaborative pursuit to understand how cells maintain redox homeostasis and how perturbations to this process result in complex diseases such as cancer, cardiovascular, and neurodegenerative disorders. This research also advances a fundamental understanding of redox regulation, which is important in cellular growth, development, aging, and cell death. Since its inception, the RBC has been and remains an internationally recognized leader in redox biology and has developed innovative, multi-disciplinary, multi-campus, and international research and education programs. The Center continues to mentor new investigators and develop research infrastructure to advance all aspects of the basic and translational questions surrounding redox biology in health and disease. The Center maintains a critical mass of NIH- and NSF-funded research in diverse fields and provides unique service and training opportunities in this area.