Marjorie F. Lou, PhD
Phone: (402) 472-0307
1.Biochemical mechanism of senile cataract formation, with emphasis in oxidation damage and repair of the lens proteins/enzymes.
2.Redox homeostasis in the lens, with emphasis in studying the physiological role of the key redox regulators of GSH-dependent thioltransferase,and the NADPH-dependent thioredoxin/thioredoxin reductase systems.
3.Redox signaling in the lens and cornea, with emphasis in the physiological role of reactive oxygen species in mediating growth factor induced cell proliferation and wound healing.